The Wei Lab @ Brigham and Women's Hospital
fibroblasts, spatial transcriptomics, and organoids.
The Wei Lab @ Brigham and Women's Hospital
fibroblasts, spatial transcriptomics, and organoids.
About The WeI Lab
Who are we?
Lab update 1/16/2026
We are a functional genomics lab at Brigham and Women's Hospital.. We employ single-cell RNA-sequencing, spatial transcriptomics, and patient-derived organoids to decipher the stromal context of inflammatory and fibrotic diseases.
Lab update 1/16/2026
Lab update 1/16/2026
Congratulations Kartik Bhamidipati and Alexa McIntyre, for publishing their study on defining the cellular and molecular mechanisms of refractory rheumatoid arthritis in Nature Immunology!
Lab Update 12/13/2025
A preprint of our story on how fibroblasts sense cell density to restore synovial lining during rheumatoid arthritis remission is now online!
Lab Update 11/21/2025
In collaboration with Sami Farhi and Britt Good, our imaging spatial transcriptomics benchmarking paper is online in Nature Communications
Lab Update 11/4/2025
In collaboration with Shruti Gupta, Deepak Rao, and Lennard Ostendorf, we are excited to share a preprint of Alvin and Lennard's manuscript on spatial transcriptomics analysis of checkpoint-inhibitor-induced interstitial nephritis.
Lab Update 3/25/2025
A preprint of Kseniia's manuscript on spatial transcriptomics analysis of immune and stromal niches in dermatomyositis and cutaneous lupus is now online!