The Wei Lab

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Scleroderma project

The Wei Lab

The Wei LabThe Wei LabThe Wei Lab
Home
Lab members
Our Science
Funding
Lab Photos
Scleroderma project
More
  • Home
  • Lab members
  • Our Science
  • Funding
  • Lab Photos
  • Scleroderma project
  • Home
  • Lab members
  • Our Science
  • Funding
  • Lab Photos
  • Scleroderma project

Our Science: Spatial reconstruction of inflammatory diseases

Wei lab "origin" stories

Papers from Kevin when he was a post-doc in Michael Brenner's lab. This is where the journey into fibroblast pathology started for the lab. According to Google AI, an origin story is "a foundational narrative that explains how a person began and developed into who they are today". Similarly, these studies shaped our lab's thinking on the topics of fibroblast biology and the use of genomic tools to query fibroblast pathology in target tissues affected by diseases.

Title slide on defining inflammatory cell states in rheumatoid arthritis using advanced molecular techniques.

with Fan Zhang

the first single-cell study of RA synovium

Article title on Notch signalling's role in fibroblast identity and arthritis.

With Ilya

scRNAseq analysis of fibroblast differentiation in RA

Title and authorship of a clinical review on fibroblast pathology in inflammatory diseases.

with Hung and Michael

a review on fibroblast pathology and how to target fibroblasts in inflammatory diseases

with Ilya, Mathilde, and Edy

comparing fibroblast subsets across inflammatory diseases

with the NIH/FNIH AMP RA/SLE Consortium

The first single-cell atlas of RA synovium


Lab publications from 2026

Ksenia and Neda

Ksenia, in collaboration with Cris and Avery

Title of a scientific article on fibroblast TGFβ signaling in rheumatoid arthritis treatment resistance.

Kartik and Alex, in collaboration with Mihir Wechalekar


Lab publications from 2025

GC and Miles, in collaboration with Sami and Britt

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The Wei Lab

60 Fenwood Road, Boston, Massachusetts 02115, United States

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